Other factor deficiencies

/Other factor deficiencies
Other factor deficiencies2018-06-15T16:29:06+00:00

A small number of Canadians, fewer than 1,000, suffer from rare factor deficiencies. These people have low levels of a specific blood protein, either factor I, II, V, VII, X, XI or XIII. Like hemophilia and VWD, these are genetic conditions for which there are treatments but no cures.

 

FACTOR OTHER NAME             INCIDENCE BLEEDING SEVERITY
Factor I fibrinogen 1 in 1,000,000           Usually mild, except with complete absence of fibrinogen
Factor II prothrombin 1 in 1,000,000 Usually mild
Factor V parahemophilia 1 in 1,000,000 Usually mild
Combined F V and F VIII           1 in 1,000,000 Usually mild
Factor VII Alexander’s 1 in 1,000,000 Severe when Factor VII levels are low
Factor VIII Hemophilia 1 in 10,000 Severe when Factor VIII levels are below 1%
Factor IX Hemophilia B 1 in 50,000 Severe when Factor IX levels are below 1%
Factor X Stuart-Prower 1 in 500,000 Moderate to severe when Factor X levels are below 10%
Factor XI Hemophilia C 1 in 100,000 Mild to moderate when Factor XI levels are below 15%
Factor XIII   1 in 3,000,000 Severe
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